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Obsessive-Compulsive Disorder in Youth and Young Adults with Depression: Clinical Characteristics of Comorbid Presentations

Research Publication Document

  • List Description

    Riddle, D. B., Guzick, A., Minhajuddin, A., Smárason, O., Armstrong, G. M., Slater, H., Mayes, T. L., Goodman, L. C., Baughn, D. L., Martin, S. L., Wakefield, S. M., Blader, J., Brown, R., Goodman, W. K., Trivedi, M. H., & Storch, E. A. (2023). Obsessive-compulsive disorder in youth and young adults with depression: Clinical characteristics of comorbid presentations. Journal of Obsessive-Compulsive and Related Disorders, 100820. https://doi.org/10.1016/j.jocrd.2023.100820 

  • Offsite Link

    https://doi.org/10.1016/j.jocrd.2023.100820
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Depressive disorders have high comorbidity with other psychiatric diagnoses. And while much is known about co-occurrences of depression and anxiety, the relationship between depression and obsessive-compulsive disorder (OCD) is not well-explored, despite depression being common in those with OCD. This study investigates the differences in symptoms between depressed youth with no comorbidities, depressed youth with anxiety, and depressed youth with OCD. Depressed youth with comorbid anxiety or OCD had higher depression severity, irritability, and insomnia. Similarly, those with comorbid OCD or anxiety had lower physical functioning, resilience, and greater difficulty in school. Further research is needed on the unique challenges presented by the comorbidity of OCD and depression.

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